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MNI 137
CAS No. 946619-21-2
MNI 137( —— )
Catalog No. M33891 CAS No. 946619-21-2
MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 103 | In Stock |
|
| 5MG | 139 | In Stock |
|
| 10MG | 170 | In Stock |
|
| 25MG | 271 | In Stock |
|
| 50MG | 402 | In Stock |
|
| 100MG | 533 | In Stock |
|
| 200MG | 705 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMNI 137
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NoteResearch use only, not for human use.
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Brief DescriptionMNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.
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DescriptionMNI137 is a potent and selective negative allosteric modulator for group II mGluRs. MNI137 has IC50s values of 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number946619-21-2
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Formula Weight341.16
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Molecular FormulaC15H9BrN4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (244.25 mM; Ultrasonic (<60°C)
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SMILESO=C1NC=2C(N=C(C1)C=3C=C(C#N)N=CC3)=CC=C(Br)C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hemstapat K, et al. A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors. J Pharmacol Exp Ther. 2007;322(1):254-264.?
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